Low impedance and highly transparent microelectrode arrays (MEA) for in vitro neuron electrical activity probing

In this study, we present the microfabrication and characterization of a transparent microelectrode array (MEA) system based on PEDOT:PSS for electrophysiology. The influence electrode dimensions impedance was investigated stability over time under physiological environment demonstrated. A very good transparency value obtained by our displaying one best transmittance values when compared to other MEA. After biocompatibility validation, successfully recorded spontaneous neuronal activity primary cortical neurons cultured 4 weeks electrodes. This work shows that microelectrodes composed are promising as new tool both electrophysiology fluorescence microscopy studies cell cultures.